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Main Article: Runes#List
- Restores in the form of regeneration, so it restores 0.6% of max health and 0.6% of max mana in 0.1 second intervals.
- Can heal up to 180% of max health and 180% of max mana when healing for the full duration.
- Can fully heal and replenish the user in 16.67 seconds.
- Health regen and mana regen bonuses which are based on maximum health or mana are not amplified by strength or intelligence.
- The buff disappears once the hero is at full health and mana.
- Damage greater than
from any player (including allies and self) or dispels the effect.
- Does not get dispelled by damage flagged as HP Removal.
- The buff of multiple Regeneration Runes does not stack, but refreshes the duration instead.