|The Bloodstone's bright ruby color is unmistakable on the battlefield, as the owner seems to have infinite vitality and spirit.|
- Bloodstone cannot be put into the backpack.
- When having multiple Bloodstones, the one in the higher inventory slot gains charges.
- The top left inventory slot has the highest priority, the bottom right one the lowest.
- The effects of Bloodstone charges from all Bloodstones a hero owns fully stack.
- Gains a charge whenever an enemy hero dies (including Reincarnation) within the radius, or whenever the owner makes a kill from any distance.
- When multiple heroes in a team have Bloodstones, each hero can gain a charge from the same enemy death.
- Each charge directly increases mana regeneration, so each charge regenerates 0.3 mana in 0.1 second intervals.
- Charges are not lost when the carrier dies with Reincarnation.
- Cannot reduce a hero's death time below 1 second.
Situational:, , , , , , , , .
Bloodstone is a niche item, generally only purchased by heroes who require intense mana regeneration, and prefer the bonus raw HP and mana instead of another item with a different active ability and weaker, but comparable regeneration bonuses.
- 's ultimate drains mana at a fixed rate based on a percentage of his total mana pool, and every spell he casts gives one attack an AoE splash, making a source of constant mana regeneration key in allowing him to farm and fight constantly.
- has a powerful AoE ultimate, able to deal out constant magical damage around him, with his only limitation being his mana and his relative fragility.
- requires Bloodstone in order to fuel his Chakrams, as they are his only source of a disable in the form of a small slowing aura which can cost up to 30 mana a second to run. Additionally, bloodstone ensures that he will always have mana to cast Timberchain to escape unfavorable fights, and the extra HP synergizes well with the large amount of armor his passive ability provides.
- will often purchase Bloodstone in order to support his ability to Rearm his spells and items, as he can quickly run out of mana simply by casting his spells, rearming, and repeating.
- and both have very similar reasons to purchase Bloodstone. They both can easily gain kills (and thus Bloodstone charges) from very far away, a large source of mana regen allows them to use their mana-expensive spells to farm, and they are extremely vulnerable to ganks, making the Pocket Deny a situationally useful last resort.
- gains bonus movement speed and attack speed from casting her spells, making a strong source of regeneration key for farming the jungle efficiently.
- is able to steal and use enemy spells. If he is against a team with particularly mana-intensive spells, Bloodstone will both give him the mana he needs to cast all the spells he steals, but also survive longer in order to cast them.
- Most heroes who want to build Bloodstone can take advantage of the ability to Disassemble to complete the Soul Booster.
- Pay close attention to which item slot your Bloodstone is in. Accidentally using Pocket Deny is easily one of the most costly misclicks possible in Dota 2.